Fumarate Vorolazan Case No. 1260141-27-2

I-Vorolazan Fumate isebenza ngokuvimbela ipompo ye-proten esiswini, ngaleyo ndlela kunciphise ukukhiqizwa kwesisusi se-gastric acid. Ngokungafani nePron Preton Prompon Evitors (PPIS), i-Vorolazan Fumate ibonise ukusungulwa okusheshayo kwesenzo nokucindezelwa kwe-acid okuqhubekayo, okwenza kube inketho esebenza ngempumelelo yokwelashwa yeziguli eziye zasabela kahle ekwelashweni njengamanje.

Enye yezinzuzo ezinkulu zeVorolazan Fumate yikhono layo lokunqoba ukulinganiselwa kweminye imishanguzo eyehlisa i-acid. Indlela yayo eyingqayizivele yesenzo iyavimbela imfihlo ye-acid ngokungaguquguquki futhi isikhathi eside, okuholela ekuphathweni kwezimpawu okungcono nokuvimbela ukuvela kwesilonda. Ngaphezu kwalokho, i-Vorolazan Fumarate ikhonjiswe ukuthi inamandla aphansi okusebenzisana kwezidakamizwa, okwenza kube yindlela ephephile yeziguli ezinama-comorbidities amaningi adinga ama-regimens ayinkimbinkimbi wezidakamizwa.

Ezifundweni zemitholampilo, i-fumarate vorolazan ikhombise ukusebenza kahle okuphakeme kuqhathaniswa ne-PPIS ekhona, ngokuqala okusheshayo kwesenzo kanye nokuvinjezelwa kwe-acid okuqhubekayo. Lokhu kusho ukuthi iziguli zingathola impumuzo esheshayo kusuka ezimpawuni ezifana ne-heartburn ne-Reflux, ukuthuthukisa ikhwalithi yempilo futhi kunciphise isidingo sokwelashwa kwemithi.