I-Palbociclib Intermediate 2-Amino-5-Bromopyriine Case No. 1072-97-5 Isithombe Esifakiwe

I-Palbociclib Intermediate 2-Amino-5-Bromopyrine Case No. 1072-97-5

Incazelo emfushane:

Ifomula ye-Molecular:C5h5BRN2

Isisindo samangqamuzana:173.01

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukufanisa

I-Palbociclib Intermediate 2-Amino-5-Bromopyrine Cas Inombolo 1072-97-5! Le mpikiswano esezingeni eliphakeme kakhulu iyingxenye ebalulekile ekuhlanganiseni kwe-palbociclib, i-kinase enamandla futhi incishisiwe ye-cyclin 4 ne-6. Ifomula ye-molecular yalomphakathi yi-C5h5BRN2 futhi isisindo samangqamuzana singu-173.01. Isetshenziswa ekukhiqizweni kwe-palbociclib, isidakamizwa esibalulekile ekulweni nomdlavuza webele.

I-PalbocicLib, eyaziwa nangokuthi i-Ibrance yegama layo yezohwebo, ibonwa kabanzi ngokusebenza kwayo ekwelapheni i-hormone receptor receptor-positing and metastatic umdlavuza webele ongemuhle noma we-metastatic. Njengengxenye esemqoka kwinqubo yokukhiqiza yePalbocicLicLicLicLicLicLicLiclib, I-2-amino-5-Bromopyrine Intermediate iyisithako esibalulekile embonini yezemithi. Ukuhlanzeka kwaso okuphezulu kanye nokwakheka kwamakhemikhali okunembile kwenza kube yisithako esibalulekile ekwenziweni kwalolumuthi osindisa impilo.

Zikhethele thina

I-JDK ingumnikazi wezindawo zokukhiqiza ezisezingeni lokuqala kanye nezinsizakusebenza zokuphathwa kwekhwalithi, eziqinisekisa ukuhlinzekwa okuzinzile kwemiphakathi ye-API. Iqembu lobuchwepheshe liqinisekisa i-R & D yomkhiqizo. Ngokumelana nakho konke, sifuna i-CMO ne-CDMO emakethe yasekhaya nakwamanye amazwe.

Okwedlule: I-3-Bromo-4-nitropyriDine Case No. 89364-04-5

Olandelayo: I-Omeprazole Intermediate 2.3.5-Trimethyl-4-NitropyriDine-N-Oxide Cas No. 86604-79-7